Mood, Food and the New Science of the

Gut-Brain Connection

The psychobiotic revolution has arrived

Looking for a way to kick the blues, quell the jitters or adjust your mood?
Then learn how to nurture your microbiome - the trillions of microbes living inside your digestive system.

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The term "psychobiotics" was coined by cofounder Ted Dinan to describe the effect of gut bacteria and other biologics on the brain through the gut-brain axis.

Along with John Cryan, they have led the development of the field of gut-brain science for almost 15 years, and are now creating their first spin out firm based on their research.

The firm will conduct R&D and commercialise a pipeline of science-based patented strains, starting with "Bifidobacterium longum APC1472" , the team's first psychobiotic.

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Bifidobacterium longum APC1472

B. longum APC1472 has promising potential as a valuable supplement in reducing specific markers of obesity and is poised to have significant relevance in conditions of heightened blood glucose, such as type 2 diabetes, as well as reducing levels of the stress hormone, cortisol.
Supporting Studies

Studies have moved from initial laboratory studies, through pre-clinical mouse trials to a large-scale human intervention trial involving 124 subjects, all described in a Lancet article below.

Human Intervention Studies

A 12 week human intervention trial involving a mixture of 124 people, both healthy, and overweight / obese, examined the impact of APC1472 on their blood sugar, waking stress and hunger levels.

In the group of healthy people who were overweight or obese, the research shows the novel bacterial strain Bifidobacterium Longum APC1472 reduced their fasting blood glucose levels and could normalise active levels of both ghrelin, a hormone signalling hunger, and the stress hormone cortisol – both of which are altered in obesity.

Fund Raising

Psychobiotics is currently in the process of forming a spin out from University College Cork (UCC), expected in Q1 2021, where UCC and the founders will share the firm’s equity.

Following this spin out, the firm will raise a seed round of 1.5 million euros to:
  • Build marketing materials for online and offline brand building
  • Manufacture and package the first capsules for sale through contract manufacturers
  • Purchase shelf space in online / offline retail channels
  • Engage full operational team to work from incubator space in UCC

The Team

Psychobiotics
Cork City
Ireland
+353 123 456 7890
contact@psychobiotics.ie
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